In Neuropathy
In a healthy person, the nerves are protected by a sheath made of a fatty substance called myelin. Vitamin B12 plays an extremely important role in both the synthesis and the maintenance of myelin, so B12 deficiency can cause the protective myelin sheath to deteriorate over time.
It exerts neuronal protection by promoting regeneration of injured nerves and antagonizing glutamate-induced neurotoxicity.
Recently several lines of evidence demonstrated that Mecobal may have potential analgesic effects in experimental and clinical studies. For example, Mecobal alleviated pain behaviors in diabetic neuropathy, low back pain and neuralgia.
Mecobal improved nerve conduction, promoted the regeneration of injured nerves, and inhibited ectopic spontaneous discharges of injured primary sensory neurons.
In addition, Mecobal improved nerve conduction in either patient of diabetic neuropathy.
In anemia
Deficiency in one or both of these vitamins causes megaloblastic anemia, a disease characterized by the presence of megaloblasts. Megaloblasts occur when inhibition of DNA synthesis causes asynchronous maturation between the nucleus and the cytoplasm. Clinical manifestations are similar to those of other types of anemia, with the exception of cobalamin deficiency megaloblastic anemia, which presents distinctive neurological symptoms.
Administering supplements of Mecobal restore body reserves of Methylcobalamin.
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